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مقاله
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Abstract
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Title:
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Biomechanical properties of early keratoconus: Suppressed deformation signal wave
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Author(s):
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Hassan Hashemi, Asghar Beiranvand, Abbasali Yekta, Amir Asharlous, Mehdi Khabazkhoob
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Mehdi Khabaz khob
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Affiliation :(optional)
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Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
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E mail:
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khabazkhoob@yahoo.com
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Phone:
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Mobile:
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09120250544
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Purpose:
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To determine the corneal biomechanical parameters with the highest diagnostic validity in early stages of keratoconus
Setting: Noor Eye Hospital, Tehran, Iran
Study design: Case Series
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Methods:
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Sixty-one eyes with a diagnosis of mild keratoconus and 61 healthy eyes participated in the study. Ocular Response Analyzer (ORA) examinations were performed for all participants and the data of the examinations, including 40 indices, were extracted and analyzed
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Results:
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The mean (SD) of keratometry and central corneal thickness in keratoconic corneas was 46.9 (2.5) and 473 (31), respectively. Of 40 evaluated indices, 32 showed a significant difference between the two groups using t-test (p<0.05). According to the results of logistic regression, the indices of H21 and CRF with R2=0.79 were the best predictors of early stages of keratoconus (p<0.001). H21 ≤190 with a sensitivity and specificity of 87% and 91.8% and CRF≤8.6 with a sensitivity and specificity of 87% and 85.3% yielded a diagnostic accuracy of 97.3% totally
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Conclusion:
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The results of this study emphasized the importance of the Peak height of the applanation signal and CRF≤8.6 among different corneal deformation signal parameters. These parameters can help to detect the corneas which are not suspicious in terms of topographic and central thickness findings but are likely to develop post lasik ectasia. Therefore, they can play an important role in completing the examinations before refractive surgery
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Attachment:
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