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مقاله
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Abstract
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Title:
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Ocular and systemic vascular adverse events following intravitreal bevacizumab
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Author(s):
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Arwa Azmeh
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Presentation Type:
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Poster
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Arwa Azmeh
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Affiliation :(optional)
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Almouassat university hospital, Damascus university
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E mail:
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arwaretina@gmail.com
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Phone:
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00963113739561
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Mobile:
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+963944363703
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Purpose:
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To review reported ocular and systemic vascular complications following intravitreal bevacizumab injection which should be considered when selecting this treatment modality
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Methods:
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MEDLINE database was searched for the past 10 years using the keyword intravitreal bevacizumab. All related articles about acular and systemic intravitreal bevacizumab side effects were chosen and used in this review.
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Results:
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The incidence of serious ocular and systemic adverse events was below 1 per 100 injections. These adverse events included: retinal artery occlusion, retinal vein occlusion, hemorrhagic macular infarction, nonarteritic anterior ischemic optic neuropathy, acute ocular ischemic syndrome associated with acute stroke, massive choroidal hemorrhage and contralateral sympathetic ophthalmia, kidney toxicity, ischemic colitis and gastrointestinal bleeding and alveolar hemorrhage.
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Conclusion:
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In case of any visual loss post intravitreal bevacizumab not attributed to reactivation of the underlying retinal or choroidal disease, one should think about possible side effects of bevacizumab on systemic, retrobulbar and ocular circulation.
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Attachment:
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