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       XXVI Annual Congress of the Iranian Society of Ophthalmology        بـیــست و ششمین کنــگــره سـالیـانه انـجـمـن چـشـم پـزشـکی ایـــران
مقاله Abstract


Title: Minimal Dose of Intravitreal Bevacizumab (0.25 mg/0.01 mL) in the Treatment of Retinopathy of Prematurity
Author(s): Alireza khodabande
Presentation Type: Oral
Subject: Posterior Segment and Uveitis
Others:
Presenting Author:
Name: Ali reza Khoda Bandeh
Affiliation :(optional) Farabi eye hospital
E mail: alireza_khodabande@yahoo.com
Phone:
Mobile: 09132137426
Purpose:

To determine whether a very low dose (0.25 mg/0.01 mL) of intravitreal bevacizumab is effective in the regression of type 1 retinopathy of prematurity (ROP).

Methods:

: This prospective, noncomparative, interventional case-series included all infants who consecutively received 0.25 mg/0.01 mL of intravitreal bevacizumab for type 1 ROP. Infants were followed up for ROP persistence/recurrence until 90 weeks’ postmenstrual age.

Results:

Forty-nine eyes of 25 consecutive infants [1-6] (24 bilateral and one unilateral) underwent an intravitreal injection of a reduced dose (0.25 mg/0.01 mL) of intravitreal bevacizumab. ROP regressed in all eyes. No plus disease/ neovascularization recurrence occurred until 90 weeks’ postmenstrual age.

Conclusion:

eyes with type 1 ROP did not have recurrent plus disease or neovascularization with 0.25mg/0.01mL intravitreal bevacizumab treatment. No safety issues were attributable to bevacizumab during the study period

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