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مقاله
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Abstract
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Title:
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Effect of smoking on retrobulbar blood flow in thyroid eye disease
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Author(s):
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A Sadeghi-Tari1, M Jamshidian-Tehrani1, A Nabavi1, S Sharif-Kashani2, E Elami1, N Hassanpour1 and KA Zamani1
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Presentation Type:
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Oral
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Subject:
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Ophthalmic Plastic and Reconstructive Surgery
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Others:
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Presenting Author:
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Name:
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Mansoreh Jamshidian Tehrani
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Affiliation :(optional)
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TUMS
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E mail:
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mansooreh_2468@yahoo.com
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Phone:
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07116304318
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Mobile:
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09171193010
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Purpose:
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To evaluate the effect of smoking
on retrobulbar blood flow parameters by
color Doppler imaging in patients with
thyroid eye disease.
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Methods:
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parameters in the
ophthalmic artery, superior ophthalmic vein,
central retinal artery, and vein were
determined by color Doppler imaging in
patients with thyroid eye disease. Patients
were grouped as smokers and non-smokers.
Never smokers and those who had stopped
smoking for at least 1 year before onset of
ophthalmopathy were considered as nonsmokers.
A thorough ophthalmic examination
including Hertel exophthalmometry was
performed. Orbital CT scan was also carried
out in all patients.
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Results:
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Fifty-one orbits from 30 patients
between 21 and 62 years old (mean±SD:
40.8±12.0) were enrolled in this study.
Smokers had greater proptosis and more
active and sever disease. (Po0.05) Muscle
involvement based on CT scan did not vary
in smokers and non-smokers. Maximum
velocity (3.78±1.74 vs 5.27±2.14, Po0.001; ttest)
and minimum velocity (1.74±0.78 vs
3.26±1.36, P =0.014; t-test) in superior
ophthalmic vein were significantly lower in
smokers than non-smokers. Even after
adjusting for age, sex, and clinical activity
score and severity, smokers had a lower
minimum velocity in superior ophthalmic
vein. (P =0.01; ANCOVA analysis).
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Conclusion:
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Cigarette smoking may correlate
with increase in orbital venous congestion in
thyroid eye disease.
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Attachment:
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