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مقاله
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Abstract
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Title:
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Intravitreal injection of expanile sulfur Hexafluoride and head maneuvering for the treatment of Vitreomacular traction
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Author(s):
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Mehdi modarreszadeh, farzaneh Agha mohammadi, Sayyed Amirpooya alemzadeh
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Presentation Type:
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Oral
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Mehdi Modarreszadeh
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Affiliation :(optional)
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Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
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E mail:
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mmodarres51@yahoo.com
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Phone:
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88074986
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Mobile:
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09121266221
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Purpose:
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To study the efficacy of a single intravitreal injection of expanile gas (SF6) in releasing vitreomacular traction.
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Methods:
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Eleven eyes of 11 patients with symptomatic and persistent VMT (>3 months duration) on spectral-domain optical coherence tomography (SD OCT) received a single intravitreal injection of 0.3 cc ml of 100% SF6 patients were instructed for head maneuvering (drinking bird maneuver). Primary outcome measure was the number of eyes with complete VMT release on OCT, 1 month following treatment. Secondary outcomes included changes in visual acuity (VA)and central retinal thickness (CFT) 1 Month following treatment.
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Results:
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Mean age (±SD) was 64.09 ±9-75 years. Eight patients (72.7%) had release of VMT was associated with NPDR in 3(27.3%) eyes with release of VMT about 100% and with BRVO and ERM in 3 eyes (27.3%) with release of VMT about 66% . Three patients who had stage II macular holes before injection progressed to stage III and IV macular hole. But one patient with lamellar hole before injection had improvement. VMT in one patient with NPDR and ERM didn’t release. Four of patients (27.3%) underwent PPV due to macular hole (3 patients 27.3%) and PRD (1 Patient 9.1%). Two of patients had diffused VMA (>1500 micron) and in one of them (50%) VMT didn’t release. Nine of patients had focal VMA (≤1500 micron) and in 7 of them VMT released (p=0.425). Mean final VA decreased 0.204 logMAR units from baseline (p=0-084). Mean CFT on SD OCT decrease by an average of 85.27 micron after injection (p=0.084).
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Conclusion:
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Intravitreal SF6 injection and head maneuvering maybe offers a minimally invasive and low cost alternative to PPV in patients with symptomatic and persistent VMT. Further studies are warranted.
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Attachment:
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