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مقاله
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Abstract
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Title:
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Comparison of two doses of intravitreal ziv-aflibercept (IVZ) vs bevacizumab (IVB) for treatment of diabetic macular edema
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Author(s):
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Ahmadreza Baghi MDMohammad Hossein Jabbarpoor Bonyadi MD Ramin Nourinia MD Masoud Soheilian, MD
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Presentation Type:
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Oral
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Ahmadreza Baghi
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Affiliation :(optional)
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. Ophthalmology Department and Ophthalmic Research Center, Labbafinejad Medical Center, school of Medicine, Shahid Beheshti University of Medical Sciences
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E mail:
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ahmadrezabaghi@yahoo.com
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Phone:
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0321 2242383
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Mobile:
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09122259433
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Purpose:
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To compare the efficacy of two doses of intravitreal ziv-aflibercept with intravitreal bevacizumab in the treatment of center involved (DME) at 12 week
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Methods:
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123 eyes with DME were randomly assigned to 3 injections of 1.25mg intravitreal ziv-aflibercept, 2.5mg intravitreal ziv-aflibercept, and 1.25mg IVB injections every 4 weeks
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Results:
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Subgroup analysis disclosed no difference in BCVA outcomes at 12 weeks among the groups in the eyes with baseline BCVA ?20/50. In the eyes with baseline BCVA <20/50 nonetheless, the improvement was significantly better at 12 weeks in the ziv-aflibercept 1.25mg group compared to the IVB group
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Conclusion:
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a stronger effect of intravitreal ziv-aflibercept compared to intravitreal bevacizumab in terms of both visual acuity improvement and macular thickness reduction was detected in the eyes with initial BCVA of less than 20/50
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Attachment:
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