The role of demographic maternal and neonatal factors, the effect of drugs and diseases are not entirely examined in congenital nasolacrimal duct obstruction. This thesis, therefore, is intended to investigate these factors among newborns in Mobini Hospital in Sabzevar, Iran.

The relevant data were obtained from 541 newborns by a checklist specific to this cross-sectional study. They were analyzed in Stata, and the prevalence of congenital nasolacrimal duct obstruction together with its relation to demographic factors was investigated.

The prevalence of congenital nasolacrimal duct obstruction (CNLDO) in the sample was 11%. However, there was no significant relationship between this disorder and such factors as mother’s job (p=0.979), maternal age (p=0.229), family history of obstruction (p=0.283), history of parental close-kin marriage (p=0.367) and residential area (p=0.774); Also, maternal age, type of delivery (p=0.729), number of pregnancies (p=0.913), history of abortions (p=0.454), and number of still-births (p=0.333) did not show any relationship with CNLDO. In addition, the disorder did not show any relationship to maternal diseases such as Arterial Blood Hypertension, Hypothyroidism, Urinarytract infection, and to the medicines taken by the mother during pregnancy. Also, no significant relationships were obtained for its incidence and factors such as neonatal weight, height, APGAR scor and head circumference. Significant relationships, however, were observed to exist between CNLDO and factors such as maternal education (p=0.003), genital infection during pregnancy (p=0.001), diabetes (p=0.024), and neonatal gender (p=0.038).

There are significant relationships between CNLDO and factors such as maternal education, genital infection during pregnancy, diabetes, and neonatal gender; however, no such relationships were observed with other factors.