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       XXVI Annual Congress of the Iranian Society of Ophthalmology        بـیــست و ششمین کنــگــره سـالیـانه انـجـمـن چـشـم پـزشـکی ایـــران
مقاله Abstract


Title: Stromal demarcation line in pulsed versus continuous light accelerated corneal cross-linking for keratoconus
Author(s): Alireza Peyman, MD; Alireza Nouralishahi, MD; Farhad Hafezi, MD, PhD; Sabine Kling, PhD; Mohamadreza Peyman, MD
Presentation Type: Oral
Subject: Cornea and Anterior Segment
Others:
Presenting Author:
Name: Alireza Peyman
Affiliation :(optional) Isfahan University of Medical Sciences
E mail: drpeyman@hotmail.com
Phone: 03134452031
Mobile: 09133271149
Purpose:

To compare the stromal demarcation line depth in pulsed versus continuous corneal cross-linking for keratoconus.

Methods:

70 eyes underwent epithelium-off cross-linking, with 0.1% riboflavin applied during 10 minutes prior to UV irradiation at 30 mW/cm2. 36 eyes received pulsed irradiation (1 second on, 1 second off) for 8 minutes, and 34 eyes underwent continuous irradiation for 4 minutes. Total fluence was 7.2 J/cm2 for both groups. Patients were evaluated at 3 months after the procedure.

Results:

We observed a significantly deeper stromal demarcation line in the pulsed group when compared to the continuous irradiation group (201.11 +/- 27.76 μm, versus 159.88 +/- 20.86 μm, p<0.001).

Conclusion:

The pulsed corneal cross-linking protocol induced a significantly deeper stromal demarcation line, when compared to the 4 minutes highly accelerated continuous cross-linking protocol. However, both CXL protocols induced a shallower demarcation line than the conventional 10 minutes continuous irradiation CXL protocol using 9 mW/cm2.

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