PXS is a systemic disease which is characterized by creation of fibro-granular materials in the anterior segment of the eye. Moreover, these materials are also found in extra ocular muscles, nerve sheath, arteries and veins of the retina, and different parts of the body. PXS is also known as a risk factor in vascular blockages in the arteries and veins of the retina, the optic nerve, and the auditory nerve.

The study was a case-control research which was performed on 100 patients referring to eye clinic. Inclusion criterion was diagnosis of PXS in patients using slit lamp and examination, while the control group didn’t have this diagnosis. Then data collection was done using questionnaires, clinical examinations, and blood experiments. Data were entered into SPSS16 and then analyzed. Significance level of P was considered ≤0.05.

: In total 100 people entered into the study. Average age of participants was 71.48 + 8.13. Average age of participants in intervention group was 71.34 + 9.96 and it was 71.62 + 5.86 in control group. Average FBS was 117.55 + 42.5, 132.96 + 52.56, and 102.14 + 18.48 milligram/deciliter in overall study, intervention, and control groups respectively. There was a significant difference in intervention and control groups regarding FBS (p=0.000). BMI of participants was 24.36 + 4.22 (in the range of 16.01-36.50) which showed a significant statistical difference in intervention and control groups (p=0.012), only the results regarding prevalence of abnormal blood sugar were significant and participants in intervention group experienced these conditions more than control group (66 percent compared to 38 percent with p=0.005).

In total, it can be concluded that despite higher prevalence of metabolic syndrome and its sub-categories in patients suffering PXS, there is no significant relationship except blood sugar.