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مقاله
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Abstract
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Title:
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Intravitreal vascular endothelial growth factor (VEGF) inhibitor injection in unrecognised early pregnancy
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Author(s):
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Farzan Kianersi, Afsaneh Naderi Beni, Heshmatollah Ghanbari, Zahra Naderi Beni
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Presentation Type:
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Poster
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Farzan Kianersi
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Affiliation :(optional)
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Isfahan University of Medical Sciences
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E mail:
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kianersi@med.mui.ac.ir
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Phone:
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03136690013
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Mobile:
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09131116083
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Purpose:
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TO report a case of inadvertently exposed to bevacizumab within the first trimester of pregnancy
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Methods:
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A 29-year-old Iranian woman presented with a deterioration of vision in the left eye (LE). She has a 10 year history of type 1 diabetes mellitus. Fundoscopy revealed
the presence of cystoid macular edema in the left eye.
The patient’s left eye was then treated with a 1.25 mg/
0.05 mL intravitreal bevacizumab injection. 18 h after the injection, she reported the vaginal bleeding
and ultrasound confirmed a 10-week pregnancy of which the patient was unaware. Patient suffered pregnancy loss.
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Results:
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Our patient was inadvertently exposed to bevacizumab within the first trimester when placental growth and fetal organogenesis take place and patient suffered pregnancy loss.
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Conclusion:
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We advise that ophthalmologists discuss pregnancy
with women of childbearing age undergoing intraocular anti-VEGF injections and in pregnant woman counselling is needed to explain the potential risks and benefits.
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Attachment:
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5387Congress 25-IVB in Pregnancy.pptx
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