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مقاله
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Abstract
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Title:
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Comparison of subclinical inflammatory response after accelerated and standard corneal cross-linking
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Author(s):
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Hassan Hashemi MD, Hossein Aghaei MD, Ebrahim Jafarzadehpur PhD, Nahid Ashraf MSc, Soheila Asgari PhD, Alireza Hedayatfar MD
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Alireza Hedayatfar
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Affiliation :(optional)
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Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran; Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran; Noor Research Center for Ophthalmic
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E mail:
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alireza28@yahoo.com
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Phone:
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02182401614
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Mobile:
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09126064677
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Purpose:
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To compare the subclinical inflammatory response induced after standard and accelerated corneal cross linking (CXL) procedures.
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Methods:
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In this comparative non-randomized interventional study, patients with progressive keratoconus who underwent standard or accelerated CXL were studied. Laser flare photometery (FM-600; Kowa, Tokyo, Japan) was used to measure anterior chamber flare preoperatively and at 1 week, 1 month, 3 months, and 6 months after the procedure.
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Results:
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Sixty eyes of 60 patients were studied; 30 eyes in standard CXL group and 30 eyes in accelerated CXL group. In both groups, the flare values were higher than baseline in all postoperative visits .The mean increase of anterior chamber flare values were 1.73 ±2.38 and 2.57 ±6.32 ph/ms (P=0.532) at 1 week, 1.72 ±1.85 and 2.02 ±3.98 ph/ms (P=0.699) at 1 month, 2.46 ±2.18 and 2.20 ±3.42 ph/ms (P=0.746) at 3 months, and 1.83 ±2.24 and 2.21 ±353 ph/ms (P=0.702) at 6 months, in the standard and accelerated CXL groups, respectively.
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Conclusion:
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Both standard and accelerated CXL procedures result in subclinical inflammatory responses that persist up to 6 months postoperatively. The amount of inflammatory response is similar between the two protocol.
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Attachment:
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