To evaluate safety, efficacy, stability of PRK in treatment of anisometropic amblyopia in non complaint children resistant to conventional therapies.

Twelve children, 6 to 17 years old, 7 with anisohypropic amblyopia, 3 with anisomyopic and 2 with astigmatic amblyopia that were noncompliant with conventional therapy such as glasses or contact lenses were treated with PRK. The examination included cycloplegic refraction, uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BCVA), biomicroscopy grading of postoperative haze, binocular vision (BV), and stereopsis were performed preoperatively and 1,3,6,12 month postopratively.

Uncorrected preooprationV.A from 0.63±0.24 logMAR reach to 0.25±0.19. and corrected preoprationV.A from 0.34±0.24 reach to 0.2±0.19 after 1 year. In repeated measures analysis UCVA and BCVA improved significantly through one year (p<0.001). BCVA increased through 3, 6, 12 months after surgery 0.83±1.75, 1.5±1.98, 1.7±2.1 lines in order . 86% of patients had 1 line or more increase in UCVA and 42% had 3 lines or more change. 66.7% of patients had 1 line and more increase in BCVA and 41% had 3 line or more after 1 year follow up. 1 patient had 1 line decrease in BCVA. The most change was seen in astigmatism group and the least change were seen in hyperopic group. Mean stereopsis was improved from 341.67±245 second of arc to 166±87.52 in 1 year follow up(p=0.018). The main complication, corneal haze was not detected.

PRK is a safe and effective treatment for anisometropic amblyopia specially for non-compliant children to conventional treatments.